Cardiac Tissue Engineering: Methods and Protocols

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Instructive Supramolecular Scaffolds for In Situ Cardiovascular Tissue Engineering

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Tissue Engineering Protocols and Methods | Springer Nature Experiments

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Recommended Offers. R2 View Offer. Decellularized scaffolds: concepts, methodologies, and applications in cardiac tissue engineering and whole-organ regeneration. In: Liu Q, Wang H, editors. Singapore: World Scientific; — Engineered heart tissue for regeneration of diseased hearts. Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies.

Am J Physiol. Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium.

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Reinecke H, Murry CE. Taking the death toll after cardiomyocyte grafting: a reminder of the importance of quantitative biology. Pore size variable type I collagen gels and their interaction with glioma cells. Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction.

Tissue Eng. Effect of injectable alginate implant on cardiac remodeling and function after recent and old infarcts in rat. Hydrogel-based engineered skeletal muscle grafts normalize heart function early after myocardial infarction. Artif Organs.


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Functional improvement of infarcted heart by co-injection of embryonic stem cells with temperature-responsive chitosan hydrogel. Tissue Eng Part A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. A synthetic non-degradable polyethylene glycol hydrogel retards adverse post-infarct left ventricular remodeling. J Card Fail. Klouda L, Mikos AG.

Biomaterials for Tissue Engineering

Thermoresponsive hydrogels in biomedical applications. Eur J Pharm Biopharm. Intra-myocardial biomaterial injection therapy in the treatment of heart failure: Materials, outcomes and challenges.

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Acta Biomater. Cells, scaffolds, and molecules for myocardial tissue engineering. Pharmacol Ther. Biomaterials for the treatment of myocardial infarction. Custom design of the cardiac microenvironment with biomaterials. Injectable biopolymers enhance angiogenesis after myocardial infarction. Reffelmann T, Kloner RA. Cellular cardiomyoplasty — cardiomyocytes, skeletal myoblasts, or stem cells for regenerating myocardium and treatment of heart failure?

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Cardiac patch constructed from human fibroblasts attenuates reduction in cardiac function after acute infarct. Extracellular matrix scaffold for cardiac repair. Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Intracoronary injection of in situ forming alginate hydrogel reverses left ventricular remodeling after myocardial infarction in Swine.

Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction.

Cardiac tissue engineering and regeneration using cell-based therapy

Experimental studies in rats. Yoshida M, Oh H. Stem cell engineering for cardiac tissue regeneration.


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  4. Cardiac Tissue Engineering - Methods and Protocols | Milica Radisic | Springer.
  5. Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering. Zimmermann WH, Eschenhagen T. Cardiac tissue engineering for replacement therapy. Heart Fail Rev. Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts. J Biomed Mater Res A. Nanowired three-dimensional cardiac patches. Nat Nanotechnol.

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    Bilodeau K, Mantovani D. Bioreactors for tissue engineering: focus on mechanical constraints. A comparative review. Cardiac tissue engineering using perfusion bioreactor systems. Nat Protoc. Design of electrical stimulation bioreactors for cardiac tissue engineering. Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Injectable self-assembling peptide nanofibers create intramyocardial microenvironments for endothelial cells. Khait L, Birla RK. Cell-based cardiac pumps and tissue-engineered ventricles.

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